Table 1. Demographic and selected breast cancer risk factors among parous participants; the Shanghai Breast Cancer Study.
Characteristic | Cases (n=3443) | Controls (n=3474) | P | ||
---|---|---|---|---|---|
n / mean 1 | % / sd 2 | n / mean 1 | % / sd 2 | ||
Study Phase | |||||
I | 1381 | 42.25 | 1495 | 44.75 | |
II | 1888 | 57.75 | 1846 | 55.25 | 0.040 |
Age (years) 3 | 49.89 | 8.13 | 50.28 | 8.68 | 0.059 |
Education | |||||
Elementary School or less | 280 | 8.57 | 420 | 12.57 | |
Junior High School | 1300 | 39.77 | 1389 | 41.57 | |
Senior High School | 1224 | 37.44 | 1174 | 35.14 | |
College or more | 465 | 14.22 | 358 | 10.72 | <.001 |
Age at Menarche | 14.42 | 1.63 | 14.68 | 1.74 | <.001 |
Menopausal Status | |||||
Premenopausal | 1970 | 60.26 | 1890 | 56.59 | |
Postmenopausal | 1299 | 39.74 | 1450 | 43.41 | 0.002 |
Age at Menopause a | 49.91 | 3.40 | 49.33 | 3.75 | <.001 |
Number of Pregnancies | |||||
1 | 693 | 21.20 | 648 | 19.40 | |
2 | 1154 | 35.30 | 1131 | 33.85 | |
3 | 775 | 23.71 | 839 | 25.11 | |
≥4 | 647 | 19.79 | 723 | 21.64 | 0.052 |
Number of Live Births | |||||
1 | 2376 | 72.68 | 2285 | 68.39 | |
2 | 629 | 19.24 | 698 | 20.89 | |
3 | 184 | 5.63 | 239 | 7.15 | |
≥4 | 80 | 2.45 | 119 | 3.56 | <.001 |
Abortion | |||||
Never | 1168 | 35.73 | 1156 | 34.60 | |
Ever | 2101 | 64.27 | 2185 | 65.40 | 0.336 |
Breastfeeding | |||||
Never | 750 | 22.94 | 689 | 20.62 | |
Ever | 2519 | 77.06 | 2652 | 79.38 | 0.022 |
Lifetime Duration of Breastfeeding (months) b | 13.2 | 11.48 | 14.85 | 12.97 | <.001 |
Breast Cancer among First Degree Relatives | |||||
Never | 3118 | 95.38 | 3249 | 97.25 | |
Ever | 151 | 4.62 | 92 | 2.75 | <.001 |
Ever had Breast Fibroadenoma | |||||
Never | 2942 | 90.25 | 3158 | 94.58 | |
Ever | 318 | 9.75 | 181 | 5.42 | <.001 |
Oral Contraceptive Use | |||||
Never | 2612 | 79.90 | 2647 | 79.23 | |
Ever | 657 | 20.10 | 694 | 20.77 | 0.497 |
Hormone Replacement Therapy | |||||
Never | 3140 | 96.11 | 3243 | 97.07 | |
Ever | 127 | 3.89 | 98 | 2.93 | 0.033 |
Body Mass Index (BMI) | 23.69 | 3.30 | 23.35 | 3.29 | <.001 |
Ever Smoking | |||||
Never | 3180 | 97.28 | 3245 | 97.13 | |
Ever | 89 | 2.72 | 96 | 2.87 | 0.710 |
Ever Drinking | |||||
Never | 3120 | 95.47 | 3152 | 94.43 | |
Ever | 148 | 4.53 | 186 | 5.57 | 0.053 |
Physical Activities in recent 10 years | |||||
Never | 2467 | 75.47 | 2330 | 69.74 | |
Ever | 802 | 24.53 | 1011 | 30.26 | <.001 |
n for categorical variables or mean for continuous variables
% for categorical variables or standard deviation(sd) for continuous variables
Age at diagnosis for cases or age at interview for controls
Among women with natural menopause
Among women who ever breastfed