Table 1.
Arterial oxygenation (PaO2), dynamic lung compliance and bronchoalveolar lavage fluid (BALF) protein data at 120 min post-surfactant treatment in all rabbits, subdivided into those treated with surface-inactive and active surfactants. Active surfactants were subdivided by surfactant composition.
Surfactant preparation | N | PaO2 (torr) | Dynamic Compliance (mL/kg/cm H2O) | BALF protein (μg/mL) |
---|---|---|---|---|
All surfactants | 109 | 346 ± 166 | 0.441 ± 0.090 | 1604 ± 1173 |
•Inactive surfactant | 14 | 89 ± 41** | 0.318 ± 0.073** | 2237 ± 1331* |
•Active surfactant: | 95 | 384 ± 141 | 0.459 ± 0.077 | 1511 ± 1126 |
◦SP-B + SP-C | 36 | 411 ± 157 | 0.474 ± 0.089 | 1604 ± 1235 |
◦SP-B | 45 | 366 ± 128 | 0.446 ± 0.069 | 1577 ± 1122 |
◦SP-C | 14 | 373 ± 136 | 0.464 ± 0.064 | 1063 ± 741 |
:P = 0.03 and
: P <0.0001 versus active surfactants