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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Kidney Int. 2015 May 20;88(4):754–763. doi: 10.1038/ki.2015.151

Figure 1. Genetic map of the targeted APOL1 regions in the NIH FSGS cohort.

Figure 1

The different functional domains composing the APOL1 protein are coded as follows: hatching for the pore-forming (p.M60-W235), dot for the membrane-addressing (p.A238-P304), and tartan for the SRA-interacting (p.A339-L398) domains. When no rs number is available in dbSNP (build 137), the chromosome position is indicated based on the GRCh37 human genome version. The amino-acid positions refer to isoform a (NP_003652, 398aa). The G1, G2 and G3 variants are labeled. For the sake of clarity, we truncated the last exon and did not represent the full 3’UTR.