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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Kidney Int. 2015 May 20;88(4):754–763. doi: 10.1038/ki.2015.151

Figure 3. EHH plots for APOL1 haplotypes in Sub-Saharan Africa (A), Yoruba from Nigeria (B), Mandenka from Senegal (C) and Bantu from Kenya (D).

Figure 3

The genome coordinates refer to the GRCh37 human genome version. APOL1 G1 (red) and to a lesser extent G2 (orange) alleles showed an enlarged LD pattern in Sub-Saharan Africa and in Yoruba populations and G2 also exhibited an extended LD pattern in Mandenkas compared to G0 (light blue), suggesting a recent positive selection in West Africa. On the contrary, APOL1 G3 allele (green) did not show conclusive evidence of long LD pattern in the Bantu population.