Table 2. The significantly up-regulated lipid metabolism-related genes in fat-1 transgenic cattle.
| GeneSymbol | Description | GenbankAccession | p-value | Fold Change |
|---|---|---|---|---|
| CYP51A1 | Bos taurus cytochrome P450,family 51,subfamily A,polypeptide 1 | NM_001025319 | 0.024 | 1.727 |
| *ACOX1 | Bos taurus acyl-CoA oxidase 1,palmitoyl | NM_001035289 | 0.019 | 1.589 |
| *SCD5 | Bos taurus stearoyl-CoA desaturase 5 | NM_001076945 | 0.010 | 1.786 |
| AGPAT4 | Bos taurus cDNA clone IMAGE:8166104 | BC114144 | 0.006 | 2.240 |
| ALOX5AP | Bos taurus arachidonate 5-lipoxygenase-activating protein | NM_001076293 | 0.033 | 1.584 |
| *LPL | Bos taurus lipoprotein lipase | NM_001075120 | 0.028 | 5.407 |
| LOC782922 | Bos taurus prostaglandin F synthetase II-like | NM_001166224 | 0.002 | 5.961 |
| MSMO1 | Bos taurus methylsterol monooxygenase 1 | NM_001098863 | 0.019 | 2.094 |
| HMGCS1 | Bos taurus HMGCS1 protein-like | NM_001206578 | 0.007 | 1.843 |
| PRODH | Bos taurus proline dehydrogenase (oxidase) 1 | NM_001075185 | 0.041 | 1.583 |
| PEX5 | Peroxisomal targeting signal 1 receptor | BT029859 | 0.002 | 8.953 |
| HMGCR | Bos taurus 3-hydroxy-3-methylglutaryl-CoA reductase | NM_001105613 | 0.002 | 1.626 |
| FDFT1 | Bos taurus farnesyl-diphosphate farnesyltransferase 1 | NM_001013004 | 0.001 | 1.692 |
| GGPS1 | Bos taurus geranylgeranyl diphosphate synthase 1 | NM_001079801 | 0.010 | 1.805 |
| CIDEA | Bos taurus cell death-inducing DFFA-like effector | NM_001083449 | 0.0164 | 1.549 |
| IFNG | Bos taurus interferon, gamma | NM_174086 | 0.0234 | 6.972 |
| NR3C1 | Bos taurus nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | NM_001206634 | 0.0352 | 2.106 |
The genes marked with an asterisk are the same as the 11 genes from the PPAR signaling pathways by the KEGG enrichment analysis.