Table 4. Arithmetic means of serum concentrations of dioxin isomers (pg TEQ/g lipid) for each age group of incinerator workers compared with the reference data obtained from the MOEJ report27).
| Dioxins | This study | Japanese general population1 | p3 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (yr old) | Ratio2 | Age (yr old) | Ratio2 | ||||||||||||||
| 20–29 (n=100) |
30–39 (n=155) |
40–49 (n=199) |
50–59 (n=184) |
>60 (n=40) |
Total (n=678) |
20–29 (n=333) |
30–39 (n=451) |
40–49 (n=496) |
50–59 (n=566) |
>60 (n=347) |
Total (n=2,264) |
||||||
| PCDDs | 4.29 | 6.07 | 8.07 | 9.20 | 8.86 | 7.35 | 42.6% | 5.04 | 5.60 | 7.48 | 10.62 | 12.01 | 8.10 | 41.8% | |||
| 2,3,7,8-TCDD | 0.66 | 0.76 | 0.95 | 1.14 | 1.13 | 0.93 | 5.4% | 0.42 | 0.52 | 0.69 | 1.38 | 1.56 | 0.91 | 4.7% | |||
| 1,2,3,7,8-PeCDD | 2.45 | 3.26 | 4.48 | 4.84 | 4.79 | 4.02 | 23.3% | 3.18 | 3.43 | 4.55 | 6.43 | 7.35 | 4.96 | 25.6% | |||
| 1,2,3,4,7,8-HxCDD | 0.12 | 0.16 | 0.20 | 0.19 | 0.18 | 0.18 | 1.0% | 0.05 | 0.06 | 0.11 | 0.19 | 0.23 | 0.13 | 0.6% | ** | ||
| 1,2,3,6,7,8-HxCDD | 1.01 | 1.56 | 1.87 | 2.15 | 1.94 | 1.75 | 10.2% | 1.08 | 1.26 | 1.66 | 2.00 | 2.17 | 1.63 | 8.4% | * | ||
| 1,2,3,7,8,9-HxCDD | 0.17 | 0.26 | 0.34 | 0.37 | 0.30 | 0.30 | 1.8% | 0.16 | 0.18 | 0.26 | 0.35 | 0.39 | 0.27 | 1.4% | * | ||
| 1,2,3,4,6,7,8-HpCDD | 0.09 | 0.12 | 0.12 | 0.14 | 0.11 | 0.12 | 0.7% | 0.11 | 0.11 | 0.14 | 0.18 | 0.19 | 0.15 | 0.8% | |||
| OCDD | 0.03 | 0.04 | 0.05 | 0.08 | 0.05 | 0.05 | 0.3% | 0.03 | 0.04 | 0.06 | 0.09 | 0.10 | 0.07 | 0.3% | |||
| PCDFs | 2.24 | 3.30 | 4.79 | 4.87 | 5.50 | 4.12 | 23.9% | 2.14 | 2.21 | 3.00 | 4.44 | 5.44 | 3.40 | 17.6% | ** | ||
| 2,3,7,8-TCDF | 0.06 | 0.07 | 0.08 | 0.09 | 0.10 | 0.08 | 0.4% | 0.06 | 0.06 | 0.09 | 0.12 | 0.13 | 0.09 | 0.5% | |||
| 1,2,3,7,8-PeCDF | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.1% | 0.00 | 0.00 | 0.00 | 0.01 | 0.02 | 0.01 | 0.0% | ** | ||
| 2,3,4,7,8-PeCDF | 1.52 | 2.02 | 2.99 | 3.20 | 3.59 | 2.64 | 15.3% | 1.51 | 1.68 | 2.29 | 3.40 | 4.24 | 2.59 | 13.4% | |||
| 1,2,3,4,7,8-HxCDF | 0.24 | 0.31 | 0.45 | 0.37 | 0.39 | 0.36 | 2.1% | 0.21 | 0.15 | 0.22 | 0.32 | 0.38 | 0.25 | 1.3% | ** | ||
| 1,2,3,6,7,8-HxCDF | 0.30 | 0.48 | 0.70 | 0.56 | 0.63 | 0.55 | 3.2% | 0.25 | 0.24 | 0.31 | 0.44 | 0.51 | 0.34 | 1.8% | ** | ||
| 1,2,3,7,8,9-HxCDF | 0.12 | 0.11 | 0.11 | 0.11 | 0.12 | 0.11 | 0.6% | 0.03 | 0.00 | 0.00 | 0.01 | 0.00 | 0.00 | 0.0% | † | ||
| 2,3,4,6,7,8-HxCDF | 0.13 | 0.25 | 0.32 | 0.26 | 0.31 | 0.26 | 1.5% | 0.04 | 0.05 | 0.07 | 0.13 | 0.15 | 0.09 | 0.4% | ** | ||
| 1,2,3,4,6,7,8-HpCDF | 0.06 | 0.08 | 0.12 | 0.08 | 0.08 | 0.09 | 0.5% | 0.03 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.1% | ** | ||
| 1,2,3,4,7,8,9-HpCDF | 0.01 | 0.01 | 0.02 | 0.01 | 0.01 | 0.01 | 0.1% | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | † | ||
| OCDF | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | † | ||
| Coplanar PCBs | 2.23 | 3.79 | 6.01 | 8.28 | 9.12 | 5.76 | 33.4% | 3.40 | 4.39 | 6.78 | 11.12 | 14.03 | 7.85 | 40.6% | |||
| Non-ortho PCBs | |||||||||||||||||
| PCB77 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | † | ||
| PCB81 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | † | ||
| PCB126 | 1.70 | 2.86 | 4.40 | 5.90 | 6.33 | 4.17 | 24.2% | 2.56 | 3.32 | 5.15 | 8.63 | 10.86 | 6.03 | 31.2% | |||
| PCB169 | 0.59 | 0.76 | 1.05 | 1.33 | 1.56 | 1.02 | 5.9% | 0.60 | 0.75 | 1.11 | 1.66 | 2.07 | 1.23 | 6.3% | |||
| Mono-ortho PCBs | |||||||||||||||||
| PCB105 | 0.02 | 0.03 | 0.05 | 0.07 | 0.07 | 0.05 | 0.3% | 0.02 | 0.03 | 0.05 | 0.08 | 0.10 | 0.06 | 0.3% | |||
| PCB114 | 0.01 | 0.01 | 0.01 | 0.02 | 0.02 | 0.01 | 0.1% | 0.01 | 0.01 | 0.02 | 0.03 | 0.04 | 0.02 | 0.1% | |||
| PCB118 | 0.10 | 0.16 | 0.24 | 0.33 | 0.37 | 0.23 | 1.4% | 0.13 | 0.17 | 0.27 | 0.43 | 0.57 | 0.31 | 1.6% | |||
| PCB123 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.0% | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.00 | 0.0% | † | ||
| PCB156 | 0.05 | 0.06 | 0.11 | 0.14 | 0.17 | 0.10 | 0.6% | 0.04 | 0.06 | 0.10 | 0.16 | 0.21 | 0.11 | 0.6% | |||
| PCB157 | 0.01 | 0.02 | 0.03 | 0.03 | 0.04 | 0.02 | 0.1% | 0.01 | 0.02 | 0.03 | 0.04 | 0.06 | 0.03 | 0.2% | |||
| PCB167 | 0.01 | 0.02 | 0.04 | 0.05 | 0.06 | 0.03 | 0.2% | 0.02 | 0.03 | 0.04 | 0.07 | 0.10 | 0.05 | 0.3% | |||
| PCB189 | 0.06 | 0.07 | 0.12 | 0.15 | 0.18 | 0.01 | 0.1% | 0.01 | 0.01 | 0.01 | 0.02 | 0.02 | 0.01 | 0.1% | |||
| Total dioxins | 8.77 | 13.16 | 18.86 | 22.35 | 23.49 | 17.23 | 100.0% | 10.58 | 12.19 | 17.25 | 26.18 | 31.47 | 19.35 | 100.0% | |||
1Serum concentrations of dioxins in the male and female general population living in all areas of Japan obtained from the MOEJ report27). 2Isomer ratios indicate the ratios of dioxin isomers to total dioxins in both this study and the MOEJ report. 3p was computed using the paired t-test for comparison of arithmetic means between this study and the MOEJ survey (*p<0.05, **p<0.01). †The t-test was not applied because the arithmetic mean value in the MOEJ survey was zero.