Table 1.
Characteristics of Schizophrenia and Non-Psychiatric Comparison Groups
| Sociodemographic | Schizophrenia (N = 88) | Non-Psychiatric Comparison Subjects (N = 71) | t or chi-square | p | ||
|---|---|---|---|---|---|---|
| M or % | SD | M or % | SD | |||
| Current Age (Years) | 49.4 | 10.8 | 50.2 | 11.5 | t = .435 | .664 |
| Education (Years) | 12.4 | 2.0 | 14.7 | 2.0 | t = 7.1 | <.001 |
| Gender (% Male) | 39.4 | - | 53.4 | - | χ2 = 3.1 | .079 |
| Race (% Caucasian) | 46.6 | - | 67.6 | - | χ2 = 7.0 | .008 |
| Marital Status (% Single, Never Married) | 62.5 | - | 29.6 | - | χ2 = 17.1 | <.001 |
| Smoking Status (% Current Smokers) | 49.4 | - | 5.6 | - | χ2 = 35.9 | <.001 |
| Age of Schizophrenia Onset (Years) | 25.8 | 11.7 | - | - | - | - |
| Duration of Illness (Years) | 23.6 | 13.3 | - | - | - | - |
| Current Antipsychotic Dose (mg CPZE/day) | 565.2 | 440.8 | - | - | - | - |
| Psychopathology and Cognition | ||||||
| Positive Symptom Factor Score | 4.3 | 3.1 | .099 | .300 | t = −12.6 | .001 |
| Negative Symptom Factor Score | 7.2 | 4.5 | 1.2 | 1.8 | t = −11.2 | .001 |
| Disorganized Symptom Factor Score | 2.3 | 1.9 | .127 | .476 | t = −10.3 | .001 |
| Executive Functioning Composite Score | -.49 | .69 | .54 | .59 | t=−9.4 | .001 |
| Comorbidity and BMI | ||||||
| CIRS Total Score | 7.1 | 5.0 | 3.1 | 3.3 | t=6.8 | .001 |
| BMI (kg/m2) | 31.0 | 8.3 | 27.7 | 7.1 | t = −3.4 | .001 |
| Lab Values | ||||||
| Fasting Blood Glucose (mg/dL) | 103.8 | 52.6 | 87.5 | 13.6 | t=2.5 | 0.013 |
| Hemoglobin A1c (%) | 6.2 | 1.2 | 5.6 | 0.3 | t=3.4 | 0.001 |
| hs-CRP (mg/L) | 4.3 | 5.4 | 2.3 | 3.8 | t = −3.9 | .001 |
Note:
BMI = Body Mass Index
CIRS = Cumulative Illness Rating Scale
CPZE = Chlorpromazine Equivalent
hs-CRP = high sensitivity C-Reactive Protein