Table 2.
Pearson Correlates of Demographic, Clinical, and Metabolic Risk Factors and hs-CRP in Schizophrenia and Non-Psychiatric Comparison Groups
Variables | hs-CRP (mg/L) in Schizophrenia (N = 88) | hs-CRP (mg/L) in Non-Psychiatric Comparison Subjects (N = 71) | ||
---|---|---|---|---|
r | p | r | p | |
Current Age (Years) | -.087 | .420 | .090 | .455 |
Education (Years) | -.016 | .881 | -.171 | .154 |
Age of Schizophrenia Onset | .106 | .333 | - | - |
Duration of Illness | -.168 | .122 | - | - |
Current Antipsychotic Dose (mg CPZE/day) | .063 | .560 | - | - |
Positive Symptom Factor Score | .046 | .669 | - | - |
Negative Symptom Factor Score | .215 | .044 | - | - |
Disorganized Symptom Factor Score | .093 | .389 | - | - |
Executive Functioning Composite Score | -.030 | .778 | -.246 | .039 |
CIRS Total Score | .264 | .013 | .117 | .332 |
BMI (kg/m2) | .317 | .006 | .661 | <.001 |
Fasting Blood Glucose (mg/dL) | .300 | .005 | .257 | .034 |
Hemoglobin A1c (%) | .406 | .001 | -.008 | .950 |
Note:
BMI = Body Mass Index
CIRS = Cumulative Illness Rating Scale
CPZE = Chlorpromazine Equivalent
hs-CRP = high sensitivity C-Reactive Protein