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. Author manuscript; available in PMC: 2016 Oct 29.
Published in final edited form as: Neuroscience. 2015 Aug 24;307:128–137. doi: 10.1016/j.neuroscience.2015.08.037

Table 1.

Summary of percent levels of Aβ, BACE1 and APP metabolites in male and female BACE1+/−·5XFAD mice at 6–7 months of age as compared with their respective 5XFAD controls

% relative to 5XFAD controls (mean ± S.E.M.)
Male BACE1+/−·5XFAD Female BACE1+/−·5XFAD
Aβ oligomers 63.8 ± 1.8 65.1 ± 2.0
Total Aβ42 50.5 ± 5.9 28.7 ± 2.4
Plaque load 33.3 ± 7.4 20.6 ± 6.0
BACE1 38.0 ± 3.4 57.9 ± 9.2
fl-APP 106.9 ± 2.6 125.2 ± 5.1
C99 51.0 ± 3.5 44.9 ± 2.2
C83 74.7 ± 5.0 72.5 ± 15.9
sAPPβ-Swe 56.7 ± 3.7 43.1 ± 4.7
sAPPα 123.0 ± 5.6 153.7 ± 5.3