Figure 4. Lysosomal function and Rag/MTORC1 promote NMJ synapse growth via Wnd/JNK signaling.
(A–D) Confocal images of larval NMJs from animals of the indicated genotypes stained with antibodies against HRP (green) and DLG (magenta). Scale bar shown in (A) also applies to (B–D).
(E) Bar graph showing the average bouton numbers in animals of the indicated genotypes.
(F–I) Confocal images of larval NMJs from animals of the indicated genotypes stained with antibodies against HRP (green) and DLG (magenta). Scale bar shown in (F) also applies to (H) and scale bar shown in (G) also applies to (I).
(J) Bar graph showing the average bouton numbers in animals of the indicated genotypes.
(K) Crosstalk between the MTORC1 and Wnd/JNK pathways.
“*”, “#”, and “¶” represent statistical significance.
