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. 2015 Oct 1;10(10):e0137794. doi: 10.1371/journal.pone.0137794

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© 2015 Laroche et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — (A) Antiproliferative activity and impact on loss of potential mitochondrial membrane with TMRM fluorescent assay (cell viability) (B) of RG7388 in parental and secondary resistant IB111, IB115 and IB128 STS cell lines. (C) Apoptosis induction analysis using FITC annexin-V and propidium iodide assay. Sensitive (IB111 and IB115) and resistant cells (IB111P4 and IB115P4) were treated 72h by RG-7388 at 1μM.