Table 3. Effect of DPP extract (Ext) on testicular markers in normal, L-T4- and PTU-treated rats.
| Experimental groups | ||||||
|---|---|---|---|---|---|---|
| Parameters (U/mg protein) | Cont. | Ext | L-T4 | L-T4 + Ext | PTU | PTU + Ext |
| SDH | 7.61 ± 0.19 | 9.04 ± 0.35 a * | 5.31 ± 0.31 a ** b ** | 8.08 ± 0.40 c ** | 5.83 ± 0.37 a ** b ** | 9.81 ± 0.65 a * d ** |
| LDH | 1.23 ± 0.05 | 1.48 ± 0.04 a ** | 0.92 ± 0.04 a ** b ** | 1.34 ± 0.09 c ** | 1.00 ± 0.05 a * b ** | 1.28 ± 0.06 b * d ** |
| ALP | 44.88 ± 3.85 | 45.40 ± 3.07 | 22.70 ± 1.16 a ** b ** | 33.10 ± 2.54 a * b * c ** | 18.08 ± 1.17 a ** b ** | 24.31 ± 1.43 a ** b ** d * |
| ACP | 24.96 ± 1.27 | 25.12 ± 1.49 | 17.15 ± 1.13 a ** b ** | 22.72 ± 1.75 c * | 15.98 ± 1.08 a ** b ** | 25.65 ± 1.35 d ** |
| AST | 20.95 ± 1.29 | 20.64 ± 0.77 | 33.21 ± 2.15 a ** b ** | 21.87 ± 1.25 c ** | 31.66 ± 1.93 a ** b ** | 20.13 ± 1.00 d * |
| ALT | 11.10 ± 0.55 | 11.33 ± 0.40 | 15.06 ± 0.64 a ** b ** | 11.51 ± 0.71 c ** | 14.05 ± 0.64 a ** b ** | 11.63 ± 0.57 d * |
| G6PD | 10.92 ± 0.44 | 10.40 ± 0.43 | 8.09 ± 0.500 a ** b ** | 9.97 ± 0.29 c ** | 6.47 ± 0.32 a ** b ** | 10.51 ± 0.45 d ** |
The data are presented as mean ± SEM (n = 10 rats/gp). The symbols
* and
** represent statistical significant at p< 0.05 and p< 0.01, respectively.
a: significant difference from normal control values,
b: significant difference from Ext values,
c: significant difference from L-T4 values and
d: significant difference from PTU values.