Table 1. Demographics and functional GI disorders (FGID) in ASD and NT siblings.
The study characteristics of the ASD and NT siblings are listed below. For categorical variables, the percent are shown in parenthesis (). For continuous variables the mean ± standard deviations are listed.
| Subject Characteristics | ASD n = 59 | NT n = 44 | P-value |
|---|---|---|---|
| Family matched | 37 | 37 | |
| Gender (Male)* | 52 (88%) | 21 (48%) | 0 |
| Age (years) | 10.3 ± 1.8 | 10.0 ± 1.8 | |
| Race/Ethnicity | |||
| White/Non-Hispanic | 49 (83%) | 33 (75%) | 0.16 |
| Hispanic | 2 (3%) | 4 (9%) | 0.13 |
| Black | 4 (7%) | 3 (7%) | 0.51 |
| Other/Unknown | 4 (7%) | 4 (9%) | 0.34 |
| FGID present (all patients) | 25 (42%) | 13 (30%) | 0.1 |
| FGID present (family matched) | 15 (41%) | 12 (32%) | 0.31 |
| H1. Vomiting and Aerophagia | |||
| H1a. Adolescent rumination syndrome | 0 | 0 | |
| H1b. Aerophagia | 2 | 2 | 0.44 |
| H1c. Cyclic Vomiting Syndrome | 0 | 1 | 0.33 |
| H2. Abdominal-pain related FGIDs | |||
| H2a. Functional Dyspepsia | 0 | 0 | |
| H2b. Irritable Bowel Syndrome | 7 | 3 | 0.21 |
| H2c. Functional Abdominal Migraine | 1 | 3 | 0.13 |
| H2d. Childhood Functional Abdominal Pain | 0 | 2 | 0.12 |
| H2d1 Childhood Functional Abdominal Pain Syndrome | 0 | 2 | 0.12 |
| H3. Constipation and fecal incontinence | |||
| Functional Constipation* | 17 | 6 | 0.035 |
| Nonretentive Fecal Incontinence | 3 | 1 | 0.3 |