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ADAM17 and type 2 angiotensin-converting enzyme (ACE2) activities in the hypothalamus of DOCA-salt hypertensive mice. The increase of hypothalamic ADAM17 activity (A) and the decrease of ACE2 activity (B) were reduced by LA treatment in DOCA-salt hypertensive mice. *P < 0.05 vs. sham and #P < 0.05 vs. DOCA. All data are means ± SE.
