Fig. 4.
LV catheterization. A and B: representative images of pressure-volume loop recordings of vehicle or ATII infusion for 28 days, respectively. The LV end-diastolic pressure (LVEDP) values were used to calculate the end-diastolic pressure-volume relationship (EDPVR) originated by pressure-volume loops with preload impediment by positive pressure ventilation and on spontaneous respiration. C: the LVDEP (expressed in mmHg) measured after 28 days of ATII or control vehicle infusion. D: the EDPVR slope values (expressed as mmHg/μl) of ATII or control vehicle infusion. E: the ESPVR slope values (expressed as mmHg/μl) of ATII or control vehicle infusion. F: the IRT time constant τ. Values are group means ± SE; N = 6–8 animals/group. *P = 0.002. &P = 0.04. #P = 0.001.