Table 1.
Summary of genes within the 5 haplotype blocks and their mRNA expression profile
| Gene (Assay ID) and Haplotype Block | Expression in Mouse Hindlimbs | Upregulated in Ischemia | C57Bl/6 > Balb/c | Balb/c > C57Bl/6 |
|---|---|---|---|---|
| Block 1 | ||||
| 3100003L05Rik (Mm01277666_m1) | No | No | No | No |
| 4933440M02Rik (Mm01277432_m1) | No | No | No | No |
| 4930571K23Rik (Mm03807449_s1) | No | No | No | No |
| Jmjd5 (Mm00513079_m1) | Yes | No | No | No |
| Nsmce1 (Mm00471126_m1) | Yes | No | No | No |
| Il4ra (Mm01275139_m1) | Yes | Yes | Yes (<2-fold) | No |
| Il21a (Mm00600319_m1) | Yes | Yes | Yes (=2-fold) | No |
| Gtf3c1 (Mm01278522_m1) | Yes | No | No | No |
| D430042009Rik (Mm00525471_m1) | Yes | No | No | No |
| Gsg1l (MM01278522_m1) | No | No | No | No |
| Xpo6 (Mm00503902_m1) | Yes | No | No | No |
| Sbk1 (Mm00455133_m1) | Yes | No | No | No |
| Lat (Mm00456761_m1) | Yes | Yes | No | No |
| Spns1 (Mm00470041_m1) | Yes | No | No | No |
| Nfatc2ip (Mm00803049_m1) | Yes | No | No | No |
| Cd19 (Mm00515420_m1) | No | No | No | No |
| Block 2 | ||||
| Bag3 (Mm00443474_m1) | Yes | No | No | No |
| Inpp5f (Mm00724391_m1) | Yes | Yes | Yes (<2-fold) | No |
| Block 3 | ||||
| ADAM12 (Mm00475719_m1) | Yes | Yes | Yes (>3-fold) | No |
| D7Ertd443e (Mm01131413_m1) | Yes | No | No | No |
| Dock1 (Mm01269874_m1) | Yes | Yes | No | No |
| Block 4 | ||||
| 9430038I01Rik (Mm03991735_g1) | Yes | Yes | No | Yes |
| Block 5 | ||||
| Gpr123 (Mm00623786_m1) | No | No | No | No |
| Kndc1 (Mm006278522_m1) | No | No | No | No |
| Utf1 (Mm00447703_g1) | No | No | No | No |
No expression was defined as no amplification or amplification at comparative threshold > 40.