FIGURE 7:

Deletion of Fyn inhibits Gas6-stimulated Schwann cell proliferation and migration. (A) Fyn^+/+ or Fyn^−/− Schwann cells were cultured for 1 or 2 d in normal medium with or without Gas6 (*p < 0.01; **p < 0.025; n = 4). (B, C) Reaggregated Fyn^+/+ or Fyn^−/− Schwann cells were allowed to migrate outward for 6 h in normal medium with or without Gas6 and stained with an antibody against S100β. The dotted circles indicate the maximum peripheries of Schwann cells migrating from the reaggregates (*p < 0.01; n = 4). Scale bar, 50 μm.