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. 2015 Oct 2;6:217. doi: 10.3389/fphar.2015.00217

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Copyright © 2015 Dong, Li, Li, Zhang, Feng, Li, Li, Tu, Han, Bai, Zhang, Niu, Ma, Xiao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Loading plots of PLS-DA between normal control group and raw HSW overdose treatment group, processed HSW overdose treatment group, chlorpromazine treatment group, respectively. Loading plots of PLS-DA between normal control group and raw HSW overdose treatment group based on bile acids in rat bile (A) and rat serum (D). Loading plots of PLS-DA between normal control group and processed HSW overdose treatment group based on bile acids in rat bile (B) and rat serum (E). Loading plots of PLS-DA between normal control group and chlorpromazine treatment group based on bile acids in rat bile (C) and rat serum (F). Blue triangles were BAs with VIP > 1 in the model.