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. Author manuscript; available in PMC: 2015 Oct 2.
Published in final edited form as: Future Oncol. 2012 Aug;8(8):961–987. doi: 10.2217/fon.12.95

Figure 5. Binding interface of trastuzumab to HER-2.

Figure 5

The crystal structure of HER-2 (red) in contact with trastuzumab (blue). The three loops that make direct contact with trastuzumab are clearly shown, depicting important binding residues.