. Author manuscript; available in PMC: 2015 Oct 2.

Published in final edited form as: Noise Health. 2014 Nov-Dec;16(73):400–409. doi: 10.4103/1463-1741.144418

Table 5b.

110 dB SPL noise exposure: Functional annotation clustering of similar GO terms relating to molecular function

MAPK tyrosine/serine/threonine phosphatase activity^*
EASE score average^a = 5.2	EASE score^b	Fold enrichment^c
GO:0017017~MAPK tyrosine/serine/ threonine phosphatase activity	7.11E-07	30.6
GO:0033549~MAPK phosphatase activity	7.11E-07	30.6
GO:0008138~protein tyrosine/serine/threonine phosphatase activity	5.91E-04	8.6
Carbohydrate binding
EASE score average^a=2.2	EASE score^b	Fold enrichment^c
GO:0005539~glycosaminoglycan binding	1.08E-03	5.0
GO:0030247~polysaccharide binding	1.77E-03	4.6
GO:0001871~pattern binding	2.63E-03	4.3
GO:0008201~heparin binding	7.97E-03	4.8
GO:0030246~carbohydrate binding	1.59E-01	1.7
Phosphatase activity
EASE score average^a=1.6	EASE score^b	Fold enrichment^c
GO:0004721~phosphoprotein phosphatase activity	5.71E-03	3.3
GO:0016791~phosphoric monoester hydrolase activity	2.69E-02	2.4
GO:0042578~phosphoric ester hydrolase activity	8.79E-02	1.9

EASE score average represents the-Log of the averaged EASE score, where 1.3 = −Log (P = 0.05),

EASE scores are the P values of a modified Fisher’s exact test. EASE score <0.05 is considered significant.

The degree of GO enrichment relative to background present on Affymetrix Mouse Genome 430 2.0 array,

Represents the most commonly shared GO term per cluster, GO = Gene ontology