Table 1. Type I error rates for evaluating dosage effects (nominal alpha = 0.05).

Model	CCRET	PLINK.all	PLINK.dup	PLINK.del
(A) Between-locus heterogeneity	0.035	0.046*	0.057	0.041
		(0.047)**	(0.053)	(0.055)
(B) Within-locus heterogeneity	0.041	0.051	0.057	0.043

*: Type I error rates based on PLINK 2-sided tests

**: Type I error rates in parentheses are based on PLINK 1-sided tests.