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. 2015 Sep 28;9:5385–5396. doi: 10.2147/DDDT.S89096

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© 2015 Mao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Ghrelin attenuates hepatocyte apoptosis in Con A-induced hepatitis.

Notes: (A) Western blots and real-time PCR evaluation of expression of Bcl-2 and Bax in liver tissues. (B) Western blotting of expression of caspase 3, 8, and 9 in liver tissues. (C) TUNEL staining showed apoptotic cells in three groups at 8 h (200×). (D) Immunohistochemistry staining (200×) showed the expression of Bcl-2 and Bax protein in liver tissue at 8 h. *P<0.05 for NC vs Con A, ^#P<0.05 for Con A vs Con A + 10 μg/kg ghrelin, and ^†P<0.05 for Con A + 50 μg/kg ghrelin vs Con A + 10 μg/kg ghrelin.

Abbreviations: Con, concanavalin; h, hours; NC, normal control; PCR, polymerase chain reaction.