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. 2015 Sep 28;9:5385–5396. doi: 10.2147/DDDT.S89096

Figure 6.

Figure 6

The protective effect of ghrelin could be interrupted by Akt kinase inhibitor.

Notes: Western blotting of expression of p-Akt; Bcl-2; Bax; and caspase 3, 8, and 9 in liver tissues. Real-time PCR evaluation of expression of Bcl-2 and Bax, and density quantification of p-Akt. *P<0.05 for NC vs Con A, #P<0.05 for Con A vs Con A + 10 μg/kg ghrelin, and P<0.05 for Con A + 10 μg/kg ghrelin + perifosine vs Con A + 10 μg/kg ghrelin.

Abbreviations: Con, concanavalin; p-Akt, phosphorylated Akt; NC, normal control; PCR, polymerase chain reaction.