Table 4.
Multivariable model of mortality following COPD exacerbation (n=36,107)
| Variable | Adjusted RR (95% CI) | P-value |
|---|---|---|
| <6 months follow-up | ||
| AKI | 1.80 (1.61, 2.03) | <0.001 |
| ≥6 months follow-up | ||
| AKI | 1.37 (1.16, 1.62) | <0.001 |
| Age at entry in years (Ref <50) | ||
| ≥50, <60 | 1.67 (1.41, 1.98) | <0.001 |
| ≥60, <70 | 2.83 (2.41, 3.34) | |
| ≥70, <80 | 4.06 (3.45, 4.78) | |
| ≥80, <90 | 5.41 (4.58, 6.38) | |
| ≥90 | 6.90 (5.70, 8.35) | |
| Sex: female | 0.89 (0.86, 0.92) | <0.001 |
| eGFR in mL/kg/1.73 m2 (Ref ≥90) | ||
| ≥60 and <90 | 0.78 (0.74, 0.83) | <0.001 |
| ≥30 and <60 | 0.88 (0.82, 0.93) | |
| ≥15 and <30 | 1.04 (0.95, 1.13) | |
| <15 | 1.02 (0.84, 1.24) | |
Abbreviations: COPD, chronic obstructive pulmonary disease; RR, risk ratio; CI, confidence interval; AKI, acute kidney injury; Ref, reference; eGFR, estimated glomerular filtration rate.