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. 2015 Oct 2;10(10):e0139369. doi: 10.1371/journal.pone.0139369

Table 4. Odds ratios for chronic kidney disease predicted by number of components of the metabolic syndrome with adjustments as described below.

Odds Ratio (95% Confidence Interval)
Model 1 Model 2 Model 3 Model 4
Adjusted for demographics Adjusted for demographics + hsCRP Adjusted for demographics + HOMA-IR Adjusted for demographics + hsCRP + HOMA-IR
0 components Ref. Ref. Ref. Ref.
1 component 2.13 (0.77–5.89) 2.90 (0.82–10.31) 2.33 (0.76–7.12) 3.62 (0.80–16.35)
2 components 2.77 (1.01–7.57) 3.78 (1.07–13.39) 2.82 (0.93–8.56) 4.31 (0.96–19.48)
3 components 3.05 (1.07–8.74) 4.54 (1.23–16.78) 2.98 (0.94–9.48) 4.90 (1.04–22.99)
4+ components 6.18*** (2.03–18.82) 9.21** (2.03–36.81) 4.98* (1.45–17.10) 7.65* (1.49–39.26)
hsCRP - 1.03 (0.99–1.07) - 1.03 (0.99–1.08)
HOMA-IR - - 1.02 (1.00–1.04) 1.02 (1.00–1.04)

Note. Demographics = age, gender, race, education, smoking and alcohol intake. hsCRP = high sensitivity C-reactive protein. HOMA-IR = Homeostasis Model Assessment insulin resistance. HDL cholesterol = high-density lipoprotein cholesterol. A p value < .01 was considered statistically significant.

*p>.05

**p < .01

***p < .001