Table 4. Odds ratios for chronic kidney disease predicted by number of components of the metabolic syndrome with adjustments as described below.
Odds Ratio (95% Confidence Interval) | ||||
---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |
Adjusted for demographics | Adjusted for demographics + hsCRP | Adjusted for demographics + HOMA-IR | Adjusted for demographics + hsCRP + HOMA-IR | |
0 components | Ref. | Ref. | Ref. | Ref. |
1 component | 2.13 (0.77–5.89) | 2.90 (0.82–10.31) | 2.33 (0.76–7.12) | 3.62 (0.80–16.35) |
2 components | 2.77 (1.01–7.57) | 3.78 (1.07–13.39) | 2.82 (0.93–8.56) | 4.31 (0.96–19.48) |
3 components | 3.05 (1.07–8.74) | 4.54 (1.23–16.78) | 2.98 (0.94–9.48) | 4.90 (1.04–22.99) |
4+ components | 6.18*** (2.03–18.82) | 9.21** (2.03–36.81) | 4.98* (1.45–17.10) | 7.65* (1.49–39.26) |
hsCRP | - | 1.03 (0.99–1.07) | - | 1.03 (0.99–1.08) |
HOMA-IR | - | - | 1.02 (1.00–1.04) | 1.02 (1.00–1.04) |
Note. Demographics = age, gender, race, education, smoking and alcohol intake. hsCRP = high sensitivity C-reactive protein. HOMA-IR = Homeostasis Model Assessment insulin resistance. HDL cholesterol = high-density lipoprotein cholesterol. A p value < .01 was considered statistically significant.
*p>.05
**p < .01
***p < .001