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Sub-mitochondrial localization of RMND1. (a) Immunofluorescence analysis of fibroblasts from control, RMND1(R417Q), and the patient. Endogenous RMND1 staining is shown in green, mitochondria are stained in red (HSP60), and the nucleus is counterstained in blue with DAPI. (b) Spatial organization of RMND1 in relation to newly synthesized mitochondrial RNA. Endogenous RMND1 staining is shown in green, BrU staining in red, and the nucleus is counterstained in blue with DAPI.
