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. Author manuscript; available in PMC: 2015 Oct 2.
Published in final edited form as: Vaccine. 2011 Dec 13;30(8):1513–1520. doi: 10.1016/j.vaccine.2011.11.072

Fig. 3.

Fig. 3

Neutralizing antibody responses against all four DEN virus serotypes following immunization with DENVax Formulations 1, 2 and 3. Groups of eight AG129 mice were immunized SC with DENVax bearing different ratios of component vaccine viruses. Additional control groups were injected by the same route only with FTA. A booster SC injection of the same range of doses was given on day 42 post-priming. Blood samples were collected at 30 and 56 days post-primary vaccination and used to measure the neutralizing antibody response to the four DEN viruses by PRNT50. Bars represent geometric mean titer (GMT) ± SE. Geometric mean titer of neutralizing antibody responses elicited in control mice immunized with FTA were lower than 40 against all four DEN virus serotypes.