Table 2.
Characteristic | ATT | Non-ATT | p |
---|---|---|---|
N | 38 | 28 | |
Age, median | 55 years | 60.5 years | 0.027 |
Sex | 1.000 | ||
Male | 14 (37%) | 10 (36%) | |
Female | 24 (63%) | 18 (64%) | |
KPS* | 0.200 | ||
80-100 | 27 (84%) | 16 (67%) | |
70 | 5 (16%) | 8 (33%) | |
Histology | 0.104 | ||
Adenocarcinoma | 25 (66%) | 13 (46%) | |
Squamous cell | 6 (16%) | 3 (11%) | |
NSCLC NOS | 7 (18%) | 12 (43%) | |
Thoracic stage | 0.390 | ||
I | 7 (18%) | 2 (7%) | |
II | 6 (16%) | 4 (14%) | |
III | 25 (66%) | 12 (79%) | |
Number of brain metastases | 1.000 | ||
1 | 19 (50%) | 14 (50%) | |
2-4 | 19 (50%) | 14 (50%) | |
Size of largest brain metastasis* | 0.495 | ||
≤ 3 cm | 30 (81%) | 25 (89%) | |
> 3 cm | 7 (19%) | 3 (11%) | |
Initial CNS therapy | 0.480 | ||
WBRT + SRS and/or Surgery | 21 (55%) | 14 (50%) | |
WBRT only or Surgery +/− SRS | 15 (39%) | 14 (50%) | |
None | 2 (5%) | 0 (0%) |
Totals do not add up due to missing data.
NOS: not otherwise specified; KPS: Karnofsky performance status; NSCLC: non-small cell lung cancer; CNS: central nervous system; WBRT: whole brain radiotherapy; SRS: stereotactic radiosurgery; ATT: aggressive thoracic therapy