Table 1. Comparison of characteristic parameters of the prior and posterior population distributions.

Prior and posterior geometric mean values and coefficients of variations (CV) are shown for nine exemplary physiological parameters.

	prior		posterior
	geometric mean val.	CV [%]	geometric mean val.	CV [%]
intP [dm/min]	3.68E-06	2841	1.76E-06	222
specCL [1/min]	0.05	204	0.017	26
specTS [1/min]	0.02	206	0.071	30
GET [min]	17.25	31	24.46	14
ITT [min]	146.4	28	183.68	18
fat vol. [L]	14.98	65	14.49	46
kidney vol. [L]	0.44	30	0.34	25
liver vol. [L]	2.36	28	2.1	30
muscle vol. [L]	32.099	26	26.35	11