Table 2. Comparison of proliferation markers (Ki67 and β-Catenin) in breast tissues adjacent to the tumor and tumor tissues of breast cancer patients based on immunohistochemistry staining.
Biomarkers | Breast tumor tissue (n = 30) | Adjacent breast tissue to tumor (n = 30) | Paired T test p<0.05 | ||||||
---|---|---|---|---|---|---|---|---|---|
Ratio (Ki67+ nucleus / total nucleus) | 6.90±4.74 | 1.18±1.19 | 0.0001 | ||||||
β-Catenin | C | C + N | N | C | C + N | N | 0.02 | ||
n = 10 | n = 18 | n = 2 | n = 19 | n = 9 | n = 2 | ||||
C (% area*) | N (% area) | C (% area) | N (% area) | ||||||
69 | 31 | 51 | 49 |
C: cytoplasma; N = nucleus; n = number of samples
* % area stained.