. 2015 Oct 2;10(10):e0138443. doi: 10.1371/journal.pone.0138443

Table 5. Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, F₂-isoprostanes and prostaglandin F_2α, α-SMA and aromatase in the breast tissues adjacent to the tumor and tumor tissues of breast cancer patients on the basis of staining intensity.

	Breast Tumor tissues		Adjacent breast Tissue to tumor
Biomarkers	n	Intensity (AU)	n	Intensity (AU)	Paired T test p<0.05
AdipoR1	27	1.30±0.63	25	1.37±0.47	ns
AdipoR2	30	1.27±0.64	29	0.86±0.36	0.022
Adiponectin	29	1.14±0.42	25	1.50±0.55	0.0023
Ob-R	30	1.57±0.49	28	1.46±0.50	ns
Leptin	30	1.80±0.32	27	1.33±0.44	0.00005
COX-1	28	1.86±0.24	26	1.69±0.43	ns
COX-2	27	0.63±0.51	24	0.33±0.44	0.009
F₂-isoprostanes	29	0.59±0.61	25	0.76±0.61	0.025
PGF_2α	29	0.72±0.65	26	1.04±1.59	0.037
α-SMA	30	1.17±0.86	27	1.67±0.49	0.02
Aromatase	26	1.50±0.58	26	1.32±0.48	ns

Results are the mean ± SEM; ns: not significant. AU = Arbitrary Unit; Adipo R1/R2 = adiponectin receptor; Ob-R = leptin receptor; COX = cyclooxygenase; PGF_2α = prostaglandin F_2α; α-SMA = α-Smooth Muscle Actin

Table 5. Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, F2-isoprostanes and prostaglandin F2α, α-SMA and aromatase in the breast tissues adjacent to the tumor and tumor tissues of breast cancer patients on the basis of staining intensity.

Table 5. Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, F₂-isoprostanes and prostaglandin F_2α, α-SMA and aromatase in the breast tissues adjacent to the tumor and tumor tissues of breast cancer patients on the basis of staining intensity.