Table 7. Correlation between staining score values of COX-2 and adipokines and their receptors, aromatase, COX-1 and PGF2α in healthy and tumor tissues as performed by Pearson test.
COX-2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Biomarkers | Breast tumor tissues (Mean±SEM: 0.70±0.42, n = 27) | Adjacent breast tissue to tumor (Mean±SEM: 0.53±0.50, n = 24) | ||||||||
Mean±SEM | N | r | ddl | p | Mean±SEM | N | r | ddl | p | |
AdipoR1 | 0.93±0.27 | 27 | 0.033 | 25 | 0.860 | 1.24±0.36 | 25 | -0.185 | 23 | 0.380 |
AdipoR2 | 0.83±0.28 | 30 | 0.000 | 28 | 1.000 | 0.83±0.34 | 29 | 0.128 | 27 | 0.510 |
Adiponectin | 0.90±0.19 | 29 | 0.174 | 27 | 0.370 | 1.15±0.46 | 25 | -0.051 | 24 | 0.800 |
Leptin | 1.07±0.12 | 30 | -0.055 | 28 | 0.770 | 1.26±0.38 | 27 | -0.239 | 25 | 0.230 |
Aromatase | 1.04±0.22 | 26 | -0.106 | 24 | 0.610 | 0.96±0.07 | 26 | 0.143 | 26 | 0.470 |
COX-1 | 1.18±0.29 | 28 | -0.389 | 26 | 0.039 | 1.38±0.47 | 26 | -0.013 | 24 | 0.950 |
PGF2α | 0.55±0.49 | 29 | -0.133 | 27 | 0.500 | 0.73±0.39 | 26 | 0.217 | 24 | 0.290 |
COX = cyclooxygenase; Adipo R1/R2 = adiponectin receptor; PGF2α = prostaglandin F2α