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. 2015 Oct 2;10(10):e0138827. doi: 10.1371/journal.pone.0138827

Table 2. Prevalence of antibodies to HSV–1 and HSV–2 at enrollment, WIHS 1994–95 cohort, by race and IFNL4 genotype (N = 1,431).

African Americans
IFNL4-ΔG/TT Genotype Total HSV–1 Positive p-value HSV–2 Positive p-value HSV–1 or HSV–2 Positive p-value
N (%) N (%)
Overall 1108 857 (77.3) 930 (83.9) - 1079 (97.4)
TT/TT 168 124 (73.8) 137 (81.5) 163 (97.0)
ΔG/TT 505 393 (77.8) 418 (82.8) 488 (96.6)
ΔG/ΔG 435 340 (78.2) 375 (86.2) 428 (98.4)
ΔG/ΔG+ΔG/TT 940 733 (78.0) 0.23 793 (84.4) 0.36 916 (97.4) 0.75
European Americans
IFNL4-ΔG/TT Genotype Total HSV–1 Positive p-value HSV–2 Positive p-value HSV–1 or HSV–2 Positive p-value
N (%) N (%) N (%)
Overall 323 185 (57.3) 201 (62.2) - 273 (84.5)
TT/TT 134 73 (54.5) 90 (67.2) 116 (86.6)
ΔG/TT 151 87 (57.6) 86 (57.0) 121 (80.1)
ΔG/ΔG 38 25 (65.8) 25 (65.8) 36 (94.7)
ΔG/ΔG+ΔG/TT 189 112 (59.3) 0.39 111 (58.7) 0.12 157 (83.1) 0.39