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. 2015 Oct 2;11(10):e1005195. doi: 10.1371/journal.ppat.1005195

Fig 7. KLF4 synergizes with BLIMP1 to activate both Rp and Zp, irrespective of the promoter methylation state.

Fig 7

A) Mock treated or methylated promoterless (empty) and Rp-673 pCpGL luciferase constructs were co-transfected into EBV-negative NOKs cells with either control vector, KLF4 vector alone, BLIMP1 vector alone, or the combination of KLF4 and BLIMP1 vectors. Luciferase activity for each of the conditions is shown; values are given as average +/- the standard deviations of results from two replicates. B) Mock treated or methylated promoterless vector and Zp-668 pCpGL luciferase constructs were co-transfected into EBV-negative NOKs cells with control vector, KLF4 vector, BLIMP1 vector or KLF4 and BLIMP1. Luciferase activity for each of the conditions is shown; values are given as average +/- the standard deviations of results from two replicates.