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. 2015 Oct 2;10(10):e0139836. doi: 10.1371/journal.pone.0139836

Table 7. Drug sensitivity and drug resistance in different drug groups of patients with community-acquired compared to nosocomial-acquired pneumonia caused by multidrug-resistant Pseudomonas aeruginosa.

Abbreviations: CAP: community-acquired pneumonia; NAP: nosocomial-acquired pneumonia; MDR Pseudomonas: multidrug resistant Pseudomonas. Note: Significant P values are shown in bold.

MDR Pseudomonas CAP (n = 27), NAP (n = 14)
Drug groups Active substance No. of tests of antibiotics on antibiogram Sensitive Intermediate Resistant ComparisonCAP + NAP
CAP NAP CAP (%) NAP (%) CAP(%) NAP (%) CAP (%) NAP (%) P value
Penicillin Piperacillin 27 14 15 (55.6) 6 (35.3) 0 0 12 (44.4) 8 (57.1) 0.741
Penicillin + β-lactamase inhibitors Piperacillin + Tazobactam 27 14 15 (55.6) 7 (50.0) 0 0 12 (44.4) 7 (50.0) 0.947
Cephalosporins Cefepime 27 14 20 (74.1) 7 (50.0) 0 0 7 (25.9) 7 (50.0) 0.304
Ceftazidime 27 13 16 (59.3) 5 (38.5) 2 (7.4) 0 9 (33.3) 8 (61.5) 0.189
Carbapenems Imipenem 27 14 11 (40.7) 7 (50.0) 1 (3.7) 0 15 (55.6) 7 (50.0) 0.687
Meropenem 26 14 12 (46.2) 6 (42.9) 3 (11.5) 1 (7.1) 11 (42.3) 7 (50.0) 0.852
Gyrase inhibitors Ciprofloxacin 27 13 8 (29.6) 4 (30.8) 0 1 (7.7) 19 (70.4) 8 (61.5) 0.336
Levofloxacin 27 14 6 (22.2) 3 (21.4) 3 (11.1) 2 (14.3) 18 (66.7) 9 (64.3) 0.956
Aminoglycosides Gentamicin 27 14 15 (55.6) 10 (71.4) 0 1 (7.1) 12 (44.4) 3 (21.4) 0.162
Tobramycin 25 12 11 (44.0) 9 (75.0) 1 (4.0) 0 13 (52.0) 3 (27.3) 0.193
Amikacin 22 11 14 (63.6) 10 (90.9) 2 (9.1) 0 6 (27.3) 1 (9.1) 0.236
Epoxide Fosfomycin 7 7 2 (28.6) 1 (14.3) 5 (71.4) 0 0 6 (85.7) 0.0035
Polymyxin Colistin 4 2 4 (100) 2 (100) 0 0 0 0 1.0