Table 5. Performance of Verigene Test in detection of drug resistant organisms.
No. of isolates | ||||||||
---|---|---|---|---|---|---|---|---|
Drug resistant Organisms | Total | Correctly Detected | Not Detected | No Call | Sensitivity (%) | 95% CI a | Specificity (%) | 95% CI a |
Gram Positive | ||||||||
MRSA | 27 | 26 | 0 | 1 | 100 | 88.8–100 | 100 | 96.6–100 |
MRSE | 4 | 4 | 0 | 0 | 100 | 54.3–100 | 100 | 97.3–100 |
VRE | 1 | 1 | 0 | 0 | 100 | 22.4–100 | 100 | 97.4–100 |
Gram Negative | ||||||||
Cefotaxime resistant Enterobacteriaceae (including ESBL producers) | 61 | 38 | 22 | 1 | 63.3 | 50.7–74.4 | 100 | 98.5–100 |
ESBL producing Enterobacteriaceae | 46 | 38 | 7 | 1 | 84.4 | 70.9–92.6 | 100 | 98.6–100 |
MDR Acinetobacter | 3 | 3 | 0 | 0 | 100 | 47.0–100 | 100 | 98.8–100 |
Carbapenem-resistant Psuedomonas | 2 | 0 | 2 | 0 | 0 | 0.0–63.1 | 100 | 98.8–100 |
Total | 98 | 72 | 24 | 2 | 75.0 | 65.4–82.6 | 100 | 98.9–100 |
MRSA: Methicillin resistant Staphylococcus aureus; MRSE: Methicillin resistant Staphylococcus epidermidis; VRE: Vancomycin resistant Enterococcus; ESBL: Extended spectrum beta-lactamase; MDR Acinetobacter: Multidrug resisant Acinetobacter
a 95% confidence interval was calculated using Adjusted Wald Method (http://www.measuringu.com/wald.htm)