Table 1. A list of tested ESCRT factors that affected HBV replication in HepG2 cells.
Complex | Suppression of HBV DNA replication |
---|---|
ESCRT-0 | si-HGS |
si-STAM1, 2 | |
ESCRT-I | si-VPS28 |
si-VPS37B* | |
si-UBAP1 | |
ESCRT-II | si-EAP20 |
si-EAP45 | |
ESCRT-III & related factors | si-CHMP4A, B* |
si-CHMP3 | |
si-CHMP2A, B | |
si-CHMP1A, B | |
si-IST1 | |
VPS4 complex | si-VPS4A |
si-VTA1* |
* The effects of VPS37B, CHMP4B and VTA1 on HBV replication are modest, yet reproducible.