Table 3.
Primary outcomes stratified by aetiology of cardiomyopathy
| Outcome | All patients (n = 510) | ICM (n = 382) | NICM (n = 128) | P-value |
|---|---|---|---|---|
| MACE | 135 (26.5) | 111 (29.1) | 24 (18.8) | 0.03 |
| Cardiac death | 76 (14.9) | 66 (17.3) | 10 (7.8) | 0.009 |
| HF hospitalization | 72 (14.1) | 55 (14.4) | 17 (13.3) | 0.88 |
| Aborted SCD | 18 (3.5) | 16 (4.2) | 2 (1.6) | 0.27 |
| Late revascularization | 13 (2.5) | 13 (3.4) | 0 (0) | 0.05 |
| Outcome | All ICM (n = 382) | CFR ≤ 1.65 (n = 280) | CFR > 1.65 (n = 102) | P-value |
| MACE | 111 (29.1) | 89 (31.8) | 22 (21.6) | 0.06 |
| Cardiac death | 66 (17.3) | 56 (20) | 10 (9.8) | 0.02 |
| HF hospitalization | 55 (14.4) | 42 (15) | 13 (12.7) | 0.63 |
| Aborted SCD | 16 (4.2) | 12 (4.3) | 4 (3.9) | 1 |
| Late revascularization | 13 (3.4) | 12 (4.3) | 1 (1.0) | 0.2 |
| Outcome | All NICM (n = 128) | CFR ≤ 1.65 (n = 60) | CFR > 1.65 (n = 68) | P-value |
| MACE | 24 (18.8) | 17 (28.3) | 7 (10.3) | 0.01 |
| Cardiac death | 10 (7.8) | 6 (10) | 4 (5.9) | 0.51 |
| HF hospitalization | 17 (13.3) | 12 (20) | 5 (7.4) | 0.04 |
| Aborted SCD | 2 (1.6) | 2 (3.3) | 0 (0) | 0.22 |
| Late revascularization | 24 (18.8) | 17 (28.3) | 7 (10.3) | 0.01 |
CFR=coronary flow reserve, HF= heart failure, ICM=ischemic cardiomyopathy, MACE=major adverse cardiovascular events, NICM=non-ischemic cardiomyopathy, SCD=sudden cardiac death.