Table 2.
Antibiotic resistance rates of enterotoxigenic Escherichia coli (ETEC) strains isolated from Peruvian children
| No. (%) of ETEC strains |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Antibiotic | Cohort 1 |
Cohort 2 |
Toxin type |
All strains | ||||||
| Diarrhoea | Control | Total | Diarrhoea | Control | Total | LT | ST | LT-ST | ||
| (n=57) | (n=26) | (n=83) | (n=63) | (n=59) | (n=122) | (n=99) | (n=63) | (n=43) | (n=205) | |
| Amp | 42 (74) | 17 (65) | 59 (71)a | 36 (57) | 36 (61) | 72 (59)a | 73 (74) | 38 (60)c | 20 (47)c | 131 (64) |
| Sxt | 35 (61) | 16 (62) | 51 (61) | 29 (46) | 27 (46) | 56 (46) | 61 (62) | 32 (51)c | 14 (33)c | 107 (52) |
| Tet | 22 (39) | 12 (46) | 34 (41) | 20 (32) | 22 (37) | 42 (34) | 34 (34) | 35 (56)c | 7 (16)c | 76 (37) |
| Amc | 11 (19) | 4 (15) | 15 (18)b | 1 (2) | 2 (3) | 3 (2)b | 12 (12) | 3 (5) | 3 (7) | 18 (9) |
| Nit | 8 (14) | 3 (12) | 11 (13) | 4 (6) | 2 (3) | 6 (5) | 5 (5) | 12 (19) | 0 | 17 (8) |
| Nal | 4 (7) | 3 (12) | 7 (8) | 7 (11) | 7 (12) | 14 (11) | 7 (7)a | 5 (8) | 9 (21)a | 21 (10) |
| Chl | 2 (4) | 3 (12) | 5 (6) | 5 (8) | 4 (7) | 9 (7) | 11 (11) | 2 (3) | 1 (2) | 14 (7) |
| Caz | 2 (4) | 0 | 2 (2) | 0 | 1 (2) | 1 (1) | 2 (2) | 0 | 1 (2) | 3 (1) |
| Gm | 0 | 0 | 0 | 0 | 1 (2) | 1 (1) | 1 (1) | 0 | 0 | 1 (0) |
| Multiresistant | 22 (39) | 12 (46) | 34 (41) | 24 (38) | 21 (36) | 45 (37) | 40 (40)a | 30 (48)a | 9 (21)a | 79 (39) |
Amc: amoxicillin-clavulanic acid; Amp: ampicillin; Caz: ceftazidime; Chl: chloramphenicol; Gm: gentamicin; LT: heat-labile toxin; Nal: nalidixic acid; Nit: nitrofurantoin; ST: heat-stabile toxin; Sxt: cotrimoxazole; Tet: tetracycline. No isolate was resistant to ciprofloxacin or cefotaxime.
a p<0.05.
b p<0.001.
c p<0.01.