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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Histopathology. 2015 Jun 4;67(6):771–782. doi: 10.1111/his.12707

Table 4. Types of esophageal epithelium directly over ESMGs and amount of ductal metaplasia associated with epithelial types.

Type of epithelium overlying each ESMG was assessed after the initial blinded scoring. In HGD/EAC cases, there were several instances where a squamous island was associated with ESMG. Those ESMGs had low-levels of ductal metaplasia. In contrast, HGD/EAC as well as SCC and ulcer were associated with ESMGs in the submucosa. Overlying epithelium could not be determined for a small number of ESMGs in the HGD/EAC group.

EAC (143 ESMGs) Non-EAC (698 ESMGs)
#
ESMGs
Mean
proportion
ductal
metaplasia
in ESMGs
# ESMGs Mean
proportion
ductal
metaplasia
in ESMGs
Squamous epithelium 74 15.6% Squamous epithelium 551 10.8%
Squamous island 17 5.4%
BE 28 11.8% BE 8 26.9%
Columnar 11 20.9%
EAC 13 37.3% SCC 58 28.3%
Gastroesophageal Junction 36 8.5%
Ulcer 11 54.4%
Peritonitis 34 5.0%