Skip to main content
. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Clin Cancer Res. 2015 Jun 12;21(19):4312–4320. doi: 10.1158/1078-0432.CCR-15-0340

Table II.

Transplantation Outcome

Summary of DLI Therapy
GVHD
Tumor Staging

Acute

UPN #
DLI
Specifics s g l Gr Late
Acute
Chronic day
+28
day
+60
day
+100
Overall
Outcome
01 3 T-Rapa Series 0 0 0 0 G N.E. SD SD PD Death (d 131) RCC
02 4 T-Rapa Series + Standard DLI (1) 1 0 0 I None V-V SD SD PD Death (d 740) RCC
03 3 T-Rapa Series 0 0 0 0 N.E. N.E. SD PD PD Death (d 134) RCC
04 7 T-Rapa Series + Standard DLI (4) 0 0 0 0 S, G, L None SD SD PD Death (d 303) Infection, GVHD, RCC
05 5 T-Rapa Series + Standard DLI (2) 0 0 0 0 N.E. N.E. SD SD PD Death (d 127) RCC
06 4 T-Rapa Series + Standard DLI (1) 0 0 0 0 S None SD SD SD Alive (d +1591)
07 2 T-Rapa #1, #2 0 0 0 0 S N.E. SD PD PD Death (d 165) RCC
08 5 T-Rapa Series + Standard DLI (2) 0 0 0 0 None None SD SD PD Death (d 300) RCC
09 4 T-Rapa Series + Standard DLI (1) 0 0 0 0 N.E. N.E. SD PD PD Death (d 143) RCC
10 1 T-Rapa #1 2 0 0 I N.E. N.E. SD PD NA Death (d 78) RCC
a

Abbreviations: T-Rapa Series, indicates patient received T-Rapa cells at day 0 of transplant and at days 14 and 45 post-transplant; Standard DLI, indicates donor lymphocyte infusion consisting of unmanipulated donor T cells; N.E., not evaluable; N.A., not applicable; S, G, L indicates skin, gut, or liver acute GVHD; V-V, indicates vulvar vaginal chronic GVHD; SD, indicates stable disease; PD, indicates progressive disease; RCC, indicates disease active at time of death (SD or PD).

b

Patients UPN07 and UPN10 did not receive all T-Rapa infusions due to poor performance status.