Table 4.
Distribution and adjusted odds ratios of asbestos exposure among women and men for the risk of lung cancer from a pooled dataset
| Gender | Exposed subjects (%) | All Lung Cancer | Lung Adenocarcinoma | Lung Squamous | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All Lung Cancer Case | Lung Adenocarcinoma | Lung Squamous | Control | |||||||||||
| n (%) | Asbestos Exposure Scorea |
n (%) | Asbestos Exposure Scorea |
n (%) | Asbestos Exposure Scorea |
n (%) | Asbestos Exposure Scorea |
OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | |
| Women and Men | 1120 (42.2) | 0.64 (1.26) | 414 (39.5) | 0.60 (1.25) | 369 (51.7) | 0.80 (1.35) | 816 (36.3) | 0.47 (1.07) | 1.10 (1.05–1.16)b | 1.42E-04 | 1.07 (1.01–1.14)b | 3.28E-02 | 1.19 (1.11–1.28)b | 6.39E-07 |
| Women | 194 (24.0) | 0.59 (1.43) | 89 (24.5) | 0.59 (1.11) | 53 (27.2) | 0.78 (1.22) | 122 (20.6) | 0.46 (0.97) | 1.06 (0.97–1.15) c | 1.98E-01 | 1.04 (0.94–1.16) c | 4.05E-01 | 1.09 (0.97–1.23) c | 1.44E-01 |
| Men | 926 (50.6) | 0.67 (1.18) | 325 (47.6) | 0.61 (1.47) | 316 (60.9) | 0.83 (1.66) | 694 (41.9) | 0.51 (1.31) | 1.16 (1.09–1.24)c | 6.98E-06 | 1.15 (1.06–1.26)c | 1.35E-03 | 1.24 (1.13–1.36)c | 4.15E-06 |
a
Mean(SD) of log-transformed exposure score
b
Odds ratios and confidence intervals were calculated for one unit of increase in the log-transformed asbestos exposure score by mixed-effects logistic regression adjusted for age, gender, smoking status, and center.
c
Odds ratios and confidence intervals were calculated for one unit of increase in the log-transformed asbestos exposure score by mixed-effects logistic regression adjusted for age, smoking status, and center.