Table 2. Multivariable Model Results.

		Baseline Methylation Measure				Time-Dependent Methylation
		Cancer Dx (n)
		No	Yes	HR (95% CI)	p	HR (95% CI)	p
IFN:
	All Cancer
	Low	222	58	Ref.		Ref.
	High	209	72	1.49 (1.01, 2.20)	0.04*	1.71 (1.16, 2.51)	0.007*
	Prostate Cancer	431	43	1.69 (1.10, 2.60)	0.02*	1.57 (1.04, 2.37)	0.03*
ICAM-1:
	All Cancer
	Low	169	44	Ref.		Ref.
	High	160	54	1.25 (0.83, 1.88)	0.29	1.17 (0.79, 1.74)	0.42
	Prostate Cancer	329	33	1.43 (1.07, 1.92)	0.02*	1.39 (1.02, 1.89)	0.04*
IL-6:
	All Cancer
	Low	213	66	Ref.		Ref.
	High	219	62	0.93 (0.65, 1.34)	0.7	0.87 (0.60, 1.24)	0.43
	Prostate Cancer	432	44	0.70 (0.51, 0.97)	0.03*	0.69 (0.50, 0.95)	0.02*
TLR2:
	All Cancer
	Low	178	49	Ref.		Ref.
	High	179	51	0.96(0.63, 1.44)	0.83	0.88 (0.59, 1.31)	0.53
	Prostate Cancer	357	35	0.88 (0.60, 1.28)	0.49	0.95 (0.66, 1.37)	0.77

^*= Statistically significant at p<0.05.