Table 8. Stable Warfarin Maintenance Dose in Different Genotypes of VKORC1 and CYP2C9 a,b,c.
| Values | SAD | P Value | |
|---|---|---|---|
| CYP2C9 b | 0.014 | ||
| 1*1* | 22 (44) | 4.2 ± 1.6 | |
| 1*2* | 6 (12) | 2.6 ± 1.2 | |
| 1*3* | 2 (4) | 2.7 ± 0.3 | |
| 2*2* | 15 (30) | 3.2 ± 1.2 | |
| 2*3* | 5 (10) | 2.4 ± 0.6 | |
| VKORC1 c | 0.002 | ||
| GG | 24 (48) | 3.9 ± 1.5 | |
| GA | 24 (48) | 2.4 ± 1.1 | |
| AA | 2 (4) | 5.6 ± 0.9 |
a Data are presented as No. (%) or Mean ± SD.
b Genotype variants for vitamin K epoxide reductase gene.
c Genotype variants for cytochrome P450 2C9.