Table 2.
Parkinson’s Dementia | |||||
---|---|---|---|---|---|
Intercept (α) | Slope in Pre(β1) | Slope in Post (β2) | Predicted Change(δ) Relative to Diagnosis | CDR Sum of Boxes at Time of Assessment | |
Epoch I – Working memory | |||||
Digit Span - Backwards* | 0.35 (0.15) | 0.01 (0.02) | −0.09 (0.02) | −5.15 (1.79) | 3 |
Mental Control* | 0.11 (0.14) | 0.02 (0.02) | −0.09 (0.03) | −4.45 (2.06) | 4 |
Epoch II – Visuospatial | |||||
Digit Symbol* | −0.57 (0.22) | −0.05 (0.03) | −0.15 (0.02) | −4.33 (1.31) | 4 |
Block Design* | 0.17 (0.14) | 0.01 (0.02) | −0.16 (0.02) | −4.32 (1.13) | 4 |
BVRT - Copy* | 0.02 (0.20) | 0.00 (0.03) | −0.14 (0.03) | −4.15 (1.67) | 4 |
Epoch III – Semantic Memory | |||||
Information* | 0.17 (0.09) | 0.04 (0.01) | −0.07 (0.02) | −2.83 (1.31) | 6 |
Non-Significant Subtests | |||||
Logical Memory | −0.05 (0.15) | 0.08 (0.05) | −0.04 (0.02) | −6.65 (1.91) | |
Associate Learning | 0.07 (0.16) | 0.03 (0.02) | −0.06 (0.02) | −4.99 (1.97) | |
Boston Naming | 0.35 (0.23) | −0.03 (0.05) | −0.07 (0.02) | −5.71 (2.85) | |
Trailmaking A | 50.52 (8.22) | 1.07 (1.58) | 2.28 (0.70) | −5.82 (2.85) | |
Digits Forward | 0.43 (0.15) | 0.00 (0.04) | −0.06 (0.02) | −4.87 (2.67) | |
Word Fluency | 0.04 (0.39) | −0.12 (0.04) | −0.08 (0.03) | −3.86 (3.25) | |
Parkinson’s No Dementia | |||||
Intercept (α) | Slope in Pre(B1) | Slope in Post (B2) | Predicted Change(δ ) Relative to Last Assessment | ||
Digit Span - Backwards | −0.06 (0.16) | −0.07 (0.02) | −0.27 (98.17) | −0.63 (0.96) | |
Mental Control | −0.28 (0.15) | −0.07 (0.02) | −0.27 (98.38) | −0.59 (0.78) | |
Digit Symbol | −1.29 (0.22) | −0.19 (0.02) | 0.23 (98.20) | −0.61 (0.83) | |
Block Design | −0.42 (0.13) | −0.08 (0.02) | −0.38 (98.83) | −0.55 (0.59) | |
BVRT-Copy | 5.05 (0.22) | −0.12 (0.03) | 2.09 (93.65) | −0.72 (0.90) | |
Information | −0.16 (0.16) | −0.06 (0.02) | 0.15 (98.82) | −0.62 (0.93) | |
Logical Memory | −0.22 (0.12) | −0.02 (0.02) | −0.27 (99.27) | −0.55 (0.58) | |
Associate Learning | −0.32 (0.15) | −0.05 (0.021) | −0.41 (98.84) | −0.56 (0.61) | |
Boston Naming | −0.25 (0.14) | −0.05 (0.02) | 0.44 (98.84) | −0.56 (0.59) | |
Trailmaking A | 58.67 (5.61) | 1.78 (0.65) | −0.68 (85.48) | −1.38 (2.00) | |
Digits Forward | −0.06 (0.12) | −0.08 (0.02) | 0.44 (98.81) | −0.55 (0.58) | |
Word Fluency | −0.54 (0.16) | −0.09 (0.02) | 0.39 (98.21) | −0.59 (0.83) |
Indicates a significant difference between Phase 1 and Phase 2