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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Alzheimer Dis Assoc Disord. 2016 Apr-Jun;30(2):127–133. doi: 10.1097/WAD.0000000000000088

Table 2.

Estimated changepoints (standard error) for each subtest by patient group

Parkinson’s Dementia
Intercept (α) Slope in Pre(β1) Slope in Post (β2) Predicted Change(δ) Relative to Diagnosis CDR Sum of Boxes at Time of Assessment
Epoch I – Working memory
Digit Span - Backwards* 0.35 (0.15) 0.01 (0.02) −0.09 (0.02) −5.15 (1.79) 3
Mental Control* 0.11 (0.14) 0.02 (0.02) −0.09 (0.03) −4.45 (2.06) 4
Epoch II – Visuospatial
Digit Symbol* −0.57 (0.22) −0.05 (0.03) −0.15 (0.02) −4.33 (1.31) 4
Block Design* 0.17 (0.14) 0.01 (0.02) −0.16 (0.02) −4.32 (1.13) 4
BVRT - Copy* 0.02 (0.20) 0.00 (0.03) −0.14 (0.03) −4.15 (1.67) 4
Epoch III – Semantic Memory
Information* 0.17 (0.09) 0.04 (0.01) −0.07 (0.02) −2.83 (1.31) 6
Non-Significant Subtests
Logical Memory −0.05 (0.15) 0.08 (0.05) −0.04 (0.02) −6.65 (1.91)
Associate Learning 0.07 (0.16) 0.03 (0.02) −0.06 (0.02) −4.99 (1.97)
Boston Naming 0.35 (0.23) −0.03 (0.05) −0.07 (0.02) −5.71 (2.85)
Trailmaking A 50.52 (8.22) 1.07 (1.58) 2.28 (0.70) −5.82 (2.85)
Digits Forward 0.43 (0.15) 0.00 (0.04) −0.06 (0.02) −4.87 (2.67)
Word Fluency 0.04 (0.39) −0.12 (0.04) −0.08 (0.03) −3.86 (3.25)
Parkinson’s No Dementia
Intercept (α) Slope in Pre(B1) Slope in Post (B2) Predicted Change(δ ) Relative to Last Assessment
Digit Span - Backwards −0.06 (0.16) −0.07 (0.02) −0.27 (98.17) −0.63 (0.96)
Mental Control −0.28 (0.15) −0.07 (0.02) −0.27 (98.38) −0.59 (0.78)
Digit Symbol −1.29 (0.22) −0.19 (0.02) 0.23 (98.20) −0.61 (0.83)
Block Design −0.42 (0.13) −0.08 (0.02) −0.38 (98.83) −0.55 (0.59)
BVRT-Copy 5.05 (0.22) −0.12 (0.03) 2.09 (93.65) −0.72 (0.90)
Information −0.16 (0.16) −0.06 (0.02) 0.15 (98.82) −0.62 (0.93)
Logical Memory −0.22 (0.12) −0.02 (0.02) −0.27 (99.27) −0.55 (0.58)
Associate Learning −0.32 (0.15) −0.05 (0.021) −0.41 (98.84) −0.56 (0.61)
Boston Naming −0.25 (0.14) −0.05 (0.02) 0.44 (98.84) −0.56 (0.59)
Trailmaking A 58.67 (5.61) 1.78 (0.65) −0.68 (85.48) −1.38 (2.00)
Digits Forward −0.06 (0.12) −0.08 (0.02) 0.44 (98.81) −0.55 (0.58)
Word Fluency −0.54 (0.16) −0.09 (0.02) 0.39 (98.21) −0.59 (0.83)
*

Indicates a significant difference between Phase 1 and Phase 2