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. 2015 Oct 3;17:134. doi: 10.1186/s13058-015-0642-8

Table 4.

Association of copy number variations with clinical variables

A. Pathological complete remission (pCR)
Gene pCR (number) No pCR (number) pCR and CNV (number) No pCR and CNV (number) P value Adjusted p value
TTK 23 28 0 8 0.02 0.95
TP53BP2 23 28 4 15 0.06 0.95
SNAI2 23 28 1 8 0.09 1.00
STK3 23 28 1 8 0.09 1.00
ABL2 23 28 7 3 0.11 1.00
B. Relapse
Gene Relapse (number) No relapse (number) Relapse and CNV (number) No relapse and CNV (number) P value Adjusted p value
SNAI2 8 32 4 1 0.03 0.14
MAPK15 8 32 5 3 0.06 0.14
TTN 8 32 0 9 0.07 0.65
PARP10 8 32 6 4 0.08 0.14
STYK1 8 32 0 7 0.11 0.77
C. BRCA proficiency
Gene BRCA mut/meth (number) BRCA proficient (number) BRCA mut/meth and CNV (number) BRCA proficient and CNV (number) P value Adjusted p value
IFT81 27 24 1 8 0.001 0.36
SNAI2 27 24 1 8 0.01 0.36
TNFAIP3 27 24 9 0 0.01 0.88
 PLCXD3 27 24 5 11 0.02 1.00
CCNB2 27 24 10 1 0.06 1.00

mut/meth mutated/methylated, CNV copy number variation