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. Author manuscript; available in PMC: 2016 Sep 18.
Published in final edited form as: J Biomech. 2015 Aug 7;48(12):3044–3051. doi: 10.1016/j.jbiomech.2015.07.029

Figure 5.

Figure 5

VSMC functional contractility increases with increasing substrate modulus. A. Bright field images show corresponding time points of variable modulus vMTF film. Red bar indicates film projection length. B. Representative temporal stress curve for 50kPa film. C. Basal tone for varying substrate moduli. Mean±SEM (n = 18, 12, 21, 20, respectively) p<0.05 compared to 1000kPa. D. Induced contractility for varying substrate moduli. Mean±SEM (n = 18, 13, 17, 14 [n = 20, 13, 21, 20], respectively [n for 50nM]). Significant with respect to substrate modulus with matching asterix color (p<0.05).