Table 1.
1H NMR (400 MHz) spectroscopic data for compounds 1–4 (acetone-d6, δ in ppm, J in Hz).
| position | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| 1 | 2.86 m | 2.90 m | 2.05 m | – |
| 2α | 1.50 m | 1.53 m | 1.50 m | 2.31 m |
| 2β | 1.71 m | 1.70 m | 1.64 m | 2.16 m |
| 3α | 1.63 m | 1.67 m | 1.66 m | 1.35 m |
| 3β | 1.91 m | 1.93 m | 1.21 m | 1.64 m |
| 4 | – | – | 1.97 m | 2.08 m |
| 5 | 2.17 m | 2.24 m | 1.88 m | 2.38 m |
| 6α | 2.17 m | 2.13 m | 1.77 m | 0.81 m |
| 6β | 1.12 m | 1.20 m | 0.90 m | 1.76 m |
| 7 | 1.95 m | 1.99 m | 1.89 m | 1.67 m |
| 8α | 2.12 m | 2.08 m | 1.82 m | 1.13 m |
| 8β | 1.45 m | 1.44 m | 1.14m | 2.05 m |
| 9α | 1.85 m | 1.70 m | 1.88 m | 2.08 m |
| 9β | 1.72 m | 1.53 m | 1.37m | 2.08 m |
| 12a | 3.28–3.33 m | 3.17–3.22 m | 3.29–3.36 m | 3.35–3.40 m |
| 12b | 3.59–3.65 m | 3.41–3.50 m | 3.40–3.50 m | 3.47–3.52 m |
| 13 | 1.25 s | 1.23 s | 0.98 s | 1.00 s |
| 14 | 1.08 s | 1.07 s | 1.10 s | 1.63 d (1.2) |
| 15 | 1.18 s | 1.20 s | 0.93 d (6.8) | 0.88 d (7.2) |
| 12-OH | 3.50–3.56 m | 3.54–3.60 m | ||
| 13-OH | 3.12 s | |||
| 14-OH | 3.03 s | |||
| 15-OH | 3.18 s | 3.19 s |