Table II.
Staphylococcal load and abscess formation in renal tissue | |||||
---|---|---|---|---|---|
Treatment | Log10CFU g−1a | P-valueb | Reduction (Log10CFU g−1) | % Inflamed area | P-value |
Mock | 5.50 ± 0.55 | N/A | N/A | 25.7±4.93 | N/A |
miniAb-A1 | 3.87± 0.44 | 0.002 | 1.63 | 6.39±1.95 | 0.00014 |
Means ± st.dev. of staphylococcal load as Log10CFU g−1 in homogenized renal tissues 10 days after infection in cohorts of 6 BALB/c mice per group. A representative of two independent animal experiments is shown.
Statistical significance was calculated with the unpaired two-tailed Students t test and P-values were recorded.
*, P<0.05.
c Reduction in bacterial load calculated as Log10CFU g−1.