Table 1.
Vaccination group | IgM | IgG | IgG1 | IgG2a | IgG2b | IgG3 |
---|---|---|---|---|---|---|
Control | 0.87 ± 0.09 | 1.10 ± 0.12 | 1.70 ± 0.34 | 1.10 ± 0.22 | 1.30 ± 0.18 | 0.87 ± 0.15 |
BCG | 0.90 ± 0.13 | 1.10 ± 0.18 | 1.80 ± 0.07 | 1.80 ± 0.20 | 1.60 ± 0.31 | 0.90 ± 0.13 |
IFN-α | 0.98 ± 0.17 | 1.50 ± 0.21 | 2.20 ± 0.22 | 1.70 ± 0.17 | 1.50 ± 0.16 | 1.14 ± 0.05 |
BCG-IFN-α | 1.20 ± 0.55 | 1.34 ± 0.69 | 1.95 ± 0.68 | 1.90 ± 0.77 | 1.82 ± 0.56 | 1.30 ± 0.55 |
Eight weeks after infection with MLM, BCG-primed/i.m. IFN-alpha boosted mice were sacrificed. Levels of antiglycolipid-1 isotype and all IgG subclasses Abs were measured in serum and determined by immunoenzymatic assay ELISA. Values are expressed as OD 450 nm and represent median ± SEM of duplicates.